2-ETHOXYNICOTINIC ACID - Names and Identifiers
2-ETHOXYNICOTINIC ACID - Physico-chemical Properties
Molecular Formula | C8H9NO3
|
Molar Mass | 167.16 |
Density | 1.231 |
Melting Point | 90-92 |
Boling Point | 297℃ |
Flash Point | 133℃ |
Vapor Presure | 0.000625mmHg at 25°C |
pKa | 3.56±0.22(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.54 |
MDL | MFCD00128788 |
2-ETHOXYNICOTINIC ACID - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
Hazard Class | IRRITANT |
2-ETHOXYNICOTINIC ACID - Introduction
2-Ethoxy nicotinic acid is an organic compound with the chemical formula C9H9NO4. The following is a description of the nature, use, preparation and safety information of 2-Ethoxy nicotinic acid:
Nature:
-Appearance: 2-Ethoxy nicotinic acid is white crystalline powder or crystal, soluble in water and organic solvents.
-Melting point: about 147-150°C.
-Chemical properties: 2-Ethoxy nicotinic acid is acidic in solution and is easily neutralized by alkali.
Use:
-Pharmaceutical field: 2-Ethoxy nicotinic acid is an important pharmaceutical intermediate that can be used to synthesize a variety of biologically active compounds. It is often used in the pharmaceutical industry to synthesize vitamin B group drugs, such as nimodipine and vitamin B1.
-Agricultural field: 2-Ethoxy nicotinic acid can be used as a raw material for fungicides and plant growth regulators to prevent and control crop diseases and promote plant growth.
Preparation Method:
- 2-Ethoxy nicotinic acid can be obtained by the reaction of nicotinic acid with ethanol. The specific preparation method includes the condensation reaction of nicotinic acid and ethanol under alkaline conditions, followed by hydrolysis to obtain the target product.
Safety Information:
- 2-Ethoxy nicotinic acid has low toxicity, but it is still necessary to pay attention to safe operation. In the process of operation, should avoid inhalation, contact with skin and ingestion. Wear appropriate protective equipment, such as goggles, gloves and laboratory coats. In case of accidental exposure or discomfort, seek medical help immediately.
- 2-Ethoxy nicotinic acid should be stored in a dry, cool, well-ventilated place, away from fire and oxidizing agents. During storage should avoid contact with air, moisture, strong acid, alkali and other harmful substances, and can take fire prevention measures and electrostatic protection measures.
Last Update:2024-04-09 15:17:57